Is the migrainous female brain different? Some new evidence.

SCN1A duplications and deletions detected in Dravet syndrome: implications for molecular diagnosis. Epilepsia 2009; 50: 1670–8. Ogiwara I, Miyamoto H, Morita N, Atapour N, Mazaki E, Inoue I, et al. Na(v)1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying a Scn1a gene mutation. J Neurosci 2007; 27: 5903–14. Oguni H, Hayashi K, Osawa M, Awaya Y, Fukuyama Y, Fukuma G, et al. Severe myoclonic epilepsy in infants. Typical and borderline groups in relation to SCN1A mutations in a Japanese cohort. In: DelgadoEscueta AV, Guerrini R, Medina MT, Genton P, Bureau M, Dravet C, editors. Advances in neurology, Myoclonic epilepsies. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 103–11. Ragona F, Granata T, Dalla Bernardina B, Offredi F, Darra F, Battaglia D, et al. Cognitive development in Dravet syndrome: a retrospective multicenter study of 26 patients. Epilepsia 2011; 52: 386–92. Ragsdale DS. How do mutant Nav1.1 sodium channels cause epilepsy? Brain Res Rev 2008; 58: 149–59. Sakauchi M, Oguni H, Kato I, Osawa M, Hirose S, et al. Mortality in Dravet syndrome: search for risk factors in Japanese patients. Epilepsia 2011; 52 (Suppl 2): 50–4. Wolff M, Cassé-Perrot C, Dravet C. Severe myoclonic epilepsy of infants (Dravet syndrome): natural history and neuropsychological findings. Epilepsia 2006; 47 (Suppl 2): 45–8. Yu FH, Mantegazza M, Westenbroek RE, Robbins CA, Kalume F, Burton KA, et al. Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. Nat Neurosci 2006; 9: 1142–9. Zuberi SM, Brunklaus A, Birch R, Reavey E, Duncan J, Forbes GH. Genotype-phenotype associations in SCN1A-related epilepsies. Neurology 2011; 76: 594–600.